Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 427.4 BDBM50380928

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50380928 (CHEMBL2016745) Show SMILES O=C(CC1CCC2(CC1)Cc1ccccc1C(=O)O2)Nc1cnc(cn1)-c1ccccc1 |(3.06,-22.71,;2.99,-21.17,;1.67,-20.37,;.32,-21.1,;.31,-22.64,;-1.01,-23.4,;-2.34,-22.63,;-2.35,-21.1,;-1.01,-20.33,;-3.68,-21.86,;-5.01,-22.63,;-6.33,-21.86,;-7.67,-22.62,;-7.67,-24.17,;-6.34,-24.94,;-5.01,-24.17,;-3.68,-24.95,;-3.67,-26.49,;-2.33,-24.17,;4.32,-20.39,;5.66,-21.14,;6.99,-20.37,;8.32,-21.14,;8.32,-22.69,;6.99,-23.46,;5.65,-22.69,;9.66,-23.46,;9.66,-25,;10.99,-25.77,;12.33,-25,;12.32,-23.45,;10.99,-22.69,)| Show InChI InChI=1S/C26H25N3O3/c30-24(29-23-17-27-22(16-28-23)19-6-2-1-3-7-19)14-18-10-12-26(13-11-18)15-20-8-4-5-9-21(20)25(31)32-26/h1-9,16-18H,10-15H2,(H,28,29,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	301	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranes				Bioorg Med Chem Lett 22: 2738-43 (2012) Article DOI: 10.1016/j.bmcl.2012.02.098 BindingDB Entry DOI: 10.7270/Q2154J34
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