Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 372.5 BDBM50051503

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50051503 (4,4-Dicyclopropyl-1-[(2S,3aS,7aS)-2-(pyrrolidine-1...) Show SMILES O=C(CCC(C1CC1)C1CC1)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C23H36N2O2/c26-22(12-11-19(16-7-8-16)17-9-10-17)25-20-6-2-1-5-18(20)15-21(25)23(27)24-13-3-4-14-24/h16-21H,1-15H2/t18-,20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity evaluated against Post-proline cleaving enzyme from Flavobacterium meningosepticum				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
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