Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 442.5 BDBM50541960

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50541960 (CHEMBL4645053) Show SMILES O=C(CCc1ccc(OCc2ccccc2)cc1)NCC1CCN(CCc2ccccc2)C1 Show InChI InChI=1S/C29H34N2O2/c32-29(30-21-27-18-20-31(22-27)19-17-24-7-3-1-4-8-24)16-13-25-11-14-28(15-12-25)33-23-26-9-5-2-6-10-26/h1-12,14-15,27H,13,16-23H2,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His6-tagged LTA4H expressed in Escherichia coli BL21 DE3 cells assessed as reduction in amino-...				ACS Med Chem Lett 11: 1244-1249 (2020) Article DOI: 10.1021/acsmedchemlett.0c00102 BindingDB Entry DOI: 10.7270/Q2FB56H6
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