Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Rho-associated protein kinase 2
(Homo sapiens (Human)) | BDBM50235400
(CHEMBL4093545)Show SMILES O=C(CNC(=O)c1ccc(cc1)-c1cnccc1OCC1CCNCC1)Nc1ccccc1 Show InChI InChI=1S/C26H28N4O3/c31-25(30-22-4-2-1-3-5-22)17-29-26(32)21-8-6-20(7-9-21)23-16-28-15-12-24(23)33-18-19-10-13-27-14-11-19/h1-9,12,15-16,19,27H,10-11,13-14,17-18H2,(H,29,32)(H,30,31) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of ROCK2 (unknown origin) |
J Med Chem 60: 2155-2161 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00033
BindingDB Entry DOI: 10.7270/Q2MC928T |
More data for this
Ligand-Target Pair | |
Maternal embryonic leucine zipper kinase
(Homo sapiens (Human)) | BDBM50235400
(CHEMBL4093545)Show SMILES O=C(CNC(=O)c1ccc(cc1)-c1cnccc1OCC1CCNCC1)Nc1ccccc1 Show InChI InChI=1S/C26H28N4O3/c31-25(30-22-4-2-1-3-5-22)17-29-26(32)21-8-6-20(7-9-21)23-16-28-15-12-24(23)33-18-19-10-13-27-14-11-19/h1-9,12,15-16,19,27H,10-11,13-14,17-18H2,(H,29,32)(H,30,31) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of MELK (unknown origin) containing kinase domain and UBA domain using STK S1 as substrate after 20 mins by HTRF assay |
J Med Chem 60: 2155-2161 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00033
BindingDB Entry DOI: 10.7270/Q2MC928T |
More data for this
Ligand-Target Pair | |