Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 468.4 BDBM50254857

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50254857 ((R)-N-(2,5-dioxo-1',3'-dihydrospiro[imidazolidine-...) Show SMILES O=C(Cn1c2ccccc2n(-c2ccccn2)c1=O)Nc1ccc2C[C@]3(Cc2c1)NC(=O)NC3=O |r| Show InChI InChI=1S/C25H20N6O4/c32-21(27-17-9-8-15-12-25(13-16(15)11-17)22(33)28-23(34)29-25)14-30-18-5-1-2-6-19(18)31(24(30)35)20-7-3-4-10-26-20/h1-11H,12-14H2,(H,27,32)(H2,28,29,33,34)/t25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair