Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 431.4 BDBM50205397

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205397 (CHEMBL3961192) Show SMILES O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C27H21N5O/c33-25(29-24-13-7-12-23(18-24)20-8-3-1-4-9-20)19-32-27(22-10-5-2-6-11-22)26(30-31-32)21-14-16-28-17-15-21/h1-18H,19H2,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair