Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50439531
(CHEMBL2418363)Show SMILES O=C(N1C[C@H]2CN(C[C@H]2C1)c1ccccn1)N1CC2CCCC(C2)C1 |r,TLB:1:16:19.20.21:23| Show InChI InChI=1S/C20H28N4O/c25-20(23-9-15-4-3-5-16(8-15)10-23)24-13-17-11-22(12-18(17)14-24)19-6-1-2-7-21-19/h1-2,6-7,15-18H,3-5,8-14H2/t15?,16?,17-,18+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human mGlu1 receptor expressed in HEK293A TREx cells assessed as calcium flux after 45 mins |
Bioorg Med Chem Lett 23: 5091-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.029
BindingDB Entry DOI: 10.7270/Q2KW5HG7 |
More data for this
Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50439531
(CHEMBL2418363)Show SMILES O=C(N1C[C@H]2CN(C[C@H]2C1)c1ccccn1)N1CC2CCCC(C2)C1 |r,TLB:1:16:19.20.21:23| Show InChI InChI=1S/C20H28N4O/c25-20(23-9-15-4-3-5-16(8-15)10-23)24-13-17-11-22(12-18(17)14-24)19-6-1-2-7-21-19/h1-2,6-7,15-18H,3-5,8-14H2/t15?,16?,17-,18+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center
Curated by ChEMBL
| Assay Description
Negative allosteric modulation of human mGlu1 receptor expressed in HEK293A TREx cells assessed as calcium flux after 45 mins |
Bioorg Med Chem Lett 23: 5091-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.029
BindingDB Entry DOI: 10.7270/Q2KW5HG7 |
More data for this
Ligand-Target Pair | |