Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 309.3 BDBM50238560

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid ceramidase (Homo sapiens (Human))	BDBM50238560 (CHEMBL4081779) Show SMILES O=C(NCCCCc1ccccc1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C18H19N3O2/c22-17(19-13-7-6-10-14-8-2-1-3-9-14)21-16-12-5-4-11-15(16)20-18(21)23/h1-5,8-9,11-12H,6-7,10,13H2,(H,19,22)(H,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...				J Med Chem 60: 5800-5815 (2017) Article DOI: 10.1021/acs.jmedchem.7b00472 BindingDB Entry DOI: 10.7270/Q2SB481G
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