Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Caspase-7
(Homo sapiens (Human)) | BDBM50002357
(CHEMBL3233626)Show InChI InChI=1S/C14H12N2O2S2/c17-13-11-5-1-2-6-12(11)20-16(13)14(18)15-8-7-10-4-3-9-19-10/h1-6,9H,7-8H2,(H,15,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of human recombinant caspase-7 using Ac-DEVD-AMC as substrate after 10 mins by fluorescence assay |
Bioorg Med Chem 22: 2416-26 (2014)
Article DOI: 10.1016/j.bmc.2014.03.002 BindingDB Entry DOI: 10.7270/Q2J38V2W |
More data for this Ligand-Target Pair | |
Caspase-3
(Homo sapiens (Human)) | BDBM50002357
(CHEMBL3233626)Show InChI InChI=1S/C14H12N2O2S2/c17-13-11-5-1-2-6-12(11)20-16(13)14(18)15-8-7-10-4-3-9-19-10/h1-6,9H,7-8H2,(H,15,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of human recombinant caspase-3 using Ac-LDEVD-AMC as substrate after 10 mins by fluorescence assay |
Bioorg Med Chem 22: 2416-26 (2014)
Article DOI: 10.1016/j.bmc.2014.03.002 BindingDB Entry DOI: 10.7270/Q2J38V2W |
More data for this Ligand-Target Pair | |