Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 414.4 BDBM50395797

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50395797 (CHEMBL2164837) Show SMILES O=C(Nc1cc(c[nH]c1=O)-c1ccncc1)[C@H](Cc1ccccc1)NCc1cnc[nH]1 |r| Show InChI InChI=1S/C23H22N6O2/c30-22-21(11-18(12-27-22)17-6-8-24-9-7-17)29-23(31)20(10-16-4-2-1-3-5-16)26-14-19-13-25-15-28-19/h1-9,11-13,15,20,26H,10,14H2,(H,25,28)(H,27,30)(H,29,31)/t20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation after 1 hr by scintillation counting				Bioorg Med Chem Lett 22: 6218-23 (2012) Article DOI: 10.1016/j.bmcl.2012.08.015 BindingDB Entry DOI: 10.7270/Q2CN751R
					More data for this Ligand-Target Pair