Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 509.5 BDBM50373769

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50373769 (CHEMBL402888) Show SMILES O=C(Nc1ccc(-c2ccccc2)n(CC2CC2)c1=O)N1CCC(CC1)n1cc([nH]c1=O)-c1ccccc1 Show InChI InChI=1S/C30H31N5O3/c36-28-25(13-14-27(23-9-5-2-6-10-23)35(28)19-21-11-12-21)31-29(37)33-17-15-24(16-18-33)34-20-26(32-30(34)38)22-7-3-1-4-8-22/h1-10,13-14,20-21,24H,11-12,15-19H2,(H,31,37)(H,32,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human recombinant CL receptor /RAMP1				Bioorg Med Chem Lett 18: 755-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.042 BindingDB Entry DOI: 10.7270/Q2T43TZ2
					More data for this Ligand-Target Pair