Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 310.3 BDBM50085278

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50085278 (CHEMBL162984 | N-[4-(2-Pyrrolidin-1-yl-ethoxy)-phe...) Show SMILES O=C(Nc1ccc(OCCN2CCCC2)cc1)c1ccccc1 Show InChI InChI=1S/C19H22N2O2/c22-19(16-6-2-1-3-7-16)20-17-8-10-18(11-9-17)23-15-14-21-12-4-5-13-21/h1-3,6-11H,4-5,12-15H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity was determined against Leukotriene A4 hydrolase				J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ
					More data for this Ligand-Target Pair