Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50117414
(1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(1H...)Show SMILES O=C(Nc1ccc2[nH]ncc2c1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C27H29N5O/c33-27(29-24-10-11-26-23(17-24)18-28-31-26)30-25-9-5-4-8-22(25)19-32-14-12-21(13-15-32)16-20-6-2-1-3-7-20/h1-11,17-18,21H,12-16,19H2,(H,28,31)(H2,29,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Inhibitory activity against recombinant human Chemokine receptor type 3 (CCR3) expressed in chinese hamster ovary cells |
J Med Chem 45: 3794-804 (2002)
BindingDB Entry DOI: 10.7270/Q2MW2GG0 |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM50117414
(1-[2-(4-Benzyl-piperidin-1-ylmethyl)-phenyl]-3-(1H...)Show SMILES O=C(Nc1ccc2[nH]ncc2c1)Nc1ccccc1CN1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C27H29N5O/c33-27(29-24-10-11-26-23(17-24)18-28-31-26)30-25-9-5-4-8-22(25)19-32-14-12-21(13-15-32)16-20-6-2-1-3-7-20/h1-11,17-18,21H,12-16,19H2,(H,28,31)(H2,29,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Inhibitory activity against human Chemokine receptor type 1 expressed in chinese hamster ovary cells |
J Med Chem 45: 3794-804 (2002)
BindingDB Entry DOI: 10.7270/Q2MW2GG0 |
More data for this
Ligand-Target Pair | |