Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Probable G-protein coupled receptor 142
(Homo sapiens (Human)) | BDBM50440703
(CHEMBL2431058)Show SMILES O=C(Nc1ncc(s1)-c1ccncc1)[C@H](Cc1ccccc1)NCc1cncs1 |r| Show InChI InChI=1S/C21H19N5OS2/c27-20(26-21-25-13-19(29-21)16-6-8-22-9-7-16)18(10-15-4-2-1-3-5-15)24-12-17-11-23-14-28-17/h1-9,11,13-14,18,24H,10,12H2,(H,25,26,27)/t18-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 734 | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio... |
ACS Med Chem Lett 4: 829-34 (2013)
Article DOI: 10.1021/ml4000854
BindingDB Entry DOI: 10.7270/Q2JM2C20 |
More data for this
Ligand-Target Pair | |
Probable G-protein coupled receptor 142
(Homo sapiens (Human)) | BDBM50440703
(CHEMBL2431058)Show SMILES O=C(Nc1ncc(s1)-c1ccncc1)[C@H](Cc1ccccc1)NCc1cncs1 |r| Show InChI InChI=1S/C21H19N5OS2/c27-20(26-21-25-13-19(29-21)16-6-8-22-9-7-16)18(10-15-4-2-1-3-5-15)24-12-17-11-23-14-28-17/h1-9,11,13-14,18,24H,10,12H2,(H,25,26,27)/t18-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio... |
ACS Med Chem Lett 4: 829-34 (2013)
Article DOI: 10.1021/ml4000854
BindingDB Entry DOI: 10.7270/Q2JM2C20 |
More data for this
Ligand-Target Pair | |