Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Serine/threonine-protein kinase D1
(Homo sapiens (Human)) | BDBM50324321
(6-(2-Cyclohexylaminopyridin-4-yl)-4-piperazin-1-yl...)Show SMILES O=C1NCc2c1cc(nc2N1CCNCC1)-c1ccnc(NC2CCCCC2)c1 Show InChI InChI=1S/C22H28N6O/c29-22-17-13-19(27-21(18(17)14-25-22)28-10-8-23-9-11-28)15-6-7-24-20(12-15)26-16-4-2-1-3-5-16/h6-7,12-13,16,23H,1-5,8-11,14H2,(H,24,26)(H,25,29) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of PKD1 by TR-FRET assay |
J Med Chem 53: 5422-38 (2010)
Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein kinase D1
(Homo sapiens (Human)) | BDBM50324321
(6-(2-Cyclohexylaminopyridin-4-yl)-4-piperazin-1-yl...)Show SMILES O=C1NCc2c1cc(nc2N1CCNCC1)-c1ccnc(NC2CCCCC2)c1 Show InChI InChI=1S/C22H28N6O/c29-22-17-13-19(27-21(18(17)14-25-22)28-10-8-23-9-11-28)15-6-7-24-20(12-15)26-16-4-2-1-3-5-16/h6-7,12-13,16,23H,1-5,8-11,14H2,(H,24,26)(H,25,29) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear export |
J Med Chem 53: 5422-38 (2010)
Article DOI: 10.1021/jm100076w
BindingDB Entry DOI: 10.7270/Q2P84C2J |
More data for this
Ligand-Target Pair | |