Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140500
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-formyl-2,3-di...)Show SMILES O=CN1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C30H31N3O2/c34-23-32-20-15-26-12-13-28(21-29(26)32)33(30(35)14-11-24-7-3-1-4-8-24)27-16-18-31(19-17-27)22-25-9-5-2-6-10-25/h1-14,21,23,27H,15-20,22H2/b14-11+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]-PYY from human NPYY2 receptor |
Bioorg Med Chem Lett 24: 430-41 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.061 BindingDB Entry DOI: 10.7270/Q2H133HQ |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50140500
((E)-N-(1-Benzyl-piperidin-4-yl)-N-(1-formyl-2,3-di...)Show SMILES O=CN1CCc2ccc(cc12)N(C1CCN(Cc2ccccc2)CC1)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C30H31N3O2/c34-23-32-20-15-26-12-13-28(21-29(26)32)33(30(35)14-11-24-7-3-1-4-8-24)27-16-18-31(19-17-27)22-25-9-5-2-6-10-25/h1-14,21,23,27H,15-20,22H2/b14-11+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Binding affinity towards the NPY Y2 receptor |
Bioorg Med Chem Lett 14: 1239-42 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.057 BindingDB Entry DOI: 10.7270/Q2M044VK |
More data for this Ligand-Target Pair | |