Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM50023768
(CHEMBL3337689)Show SMILES O=S(=O)(N1CCCc2cc(ccc12)-c1cccnc1)c1cccc(c1)C#N Show InChI InChI=1S/C21H17N3O2S/c22-14-16-4-1-7-20(12-16)27(25,26)24-11-3-6-18-13-17(8-9-21(18)24)19-5-2-10-23-15-19/h1-2,4-5,7-10,12-13,15H,3,6,11H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)
Curated by ChEMBL
| Assay Description
Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate |
J Med Chem 57: 7811-7 (2014)
Article DOI: 10.1021/jm501004t
BindingDB Entry DOI: 10.7270/Q2TQ634M |
More data for this
Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM50023768
(CHEMBL3337689)Show SMILES O=S(=O)(N1CCCc2cc(ccc12)-c1cccnc1)c1cccc(c1)C#N Show InChI InChI=1S/C21H17N3O2S/c22-14-16-4-1-7-20(12-16)27(25,26)24-11-3-6-18-13-17(8-9-21(18)24)19-5-2-10-23-15-19/h1-2,4-5,7-10,12-13,15H,3,6,11H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Saarland University and Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)
Curated by ChEMBL
| Assay Description
Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate |
J Med Chem 57: 7811-7 (2014)
Article DOI: 10.1021/jm501004t
BindingDB Entry DOI: 10.7270/Q2TQ634M |
More data for this
Ligand-Target Pair | |