Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 328.3 BDBM354767

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354767 (Preparation of 1-(1H-indol-5-yl)-6-(pyridin-4-yl)-...) Show SMILES O=c1[nH]c2ncc(nc2n1-c1ccc2[nH]ccc2c1)-c1ccncc1 Show InChI InChI=1S/C18H12N6O/c25-18-23-16-17(22-15(10-21-16)11-3-6-19-7-4-11)24(18)13-1-2-14-12(9-13)5-8-20-14/h1-10,20H,(H,21,23,25)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354767 (Preparation of 1-(1H-indol-5-yl)-6-(pyridin-4-yl)-...) Show SMILES O=c1[nH]c2ncc(nc2n1-c1ccc2[nH]ccc2c1)-c1ccncc1 Show InChI InChI=1S/C18H12N6O/c25-18-23-16-17(22-15(10-21-16)11-3-6-19-7-4-11)24(18)13-1-2-14-12(9-13)5-8-20-14/h1-10,20H,(H,21,23,25)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair