Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 354.3 BDBM50237266

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50237266 (CHEMBL4097026) Show SMILES O=c1c(nc2ccccc2n1Cc1ccccc1)-c1ccc2nonc2c1 Show InChI InChI=1S/C21H14N4O2/c26-21-20(15-10-11-16-18(12-15)24-27-23-16)22-17-8-4-5-9-19(17)25(21)13-14-6-2-1-3-7-14/h1-12H,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description In vitro inhibition of farnesyl-protein transferase				J Med Chem 60: 2401-2410 (2017) Article DOI: 10.1021/acs.jmedchem.6b01759 BindingDB Entry DOI: 10.7270/Q2SN0C70
					More data for this Ligand-Target Pair