Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 263.2 BDBM50361110

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Natural resistance-associated macrophage protein 2 (Homo sapiens (Human))	BDBM50361110 (CHEMBL1933787) Show SMILES O=c1c-2c(CCc3ccccc-23)[nH]n1-c1ccccn1 Show InChI InChI=1S/C16H13N3O/c20-16-15-12-6-2-1-5-11(12)8-9-13(15)18-19(16)14-7-3-4-10-17-14/h1-7,10,18H,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method				Bioorg Med Chem Lett 22: 90-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.069 BindingDB Entry DOI: 10.7270/Q2RJ4JX6
					More data for this Ligand-Target Pair