Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 443.4 BDBM50064080

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50064080 (2-[3-((E)-2-Quinolin-2-yl-vinyl)-phenyl]-6-(1H-tet...) Show SMILES O=c1cc(oc2ccc(cc12)-c1nnn[nH]1)-c1cccc(C=Cc2ccc3ccccc3n2)c1 |w:22.25| Show InChI InChI=1S/C27H17N5O2/c33-24-16-26(34-25-13-10-20(15-22(24)25)27-29-31-32-30-27)19-6-3-4-17(14-19)8-11-21-12-9-18-5-1-2-7-23(18)28-21/h1-16H,(H,29,30,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	307	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]-LTD4.				J Med Chem 41: 1428-38 (1998) Article DOI: 10.1021/jm970179x BindingDB Entry DOI: 10.7270/Q21835MZ
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