Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 345.3 BDBM50125430

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50125430 (3-[2-(4-Benzyl-phenoxy)-ethyl]-3,4-dihydro-imidazo...) Show SMILES O=c1ccc2ncn(CCOc3ccc(Cc4ccccc4)cc3)c2[nH]1 Show InChI InChI=1S/C21H19N3O2/c25-20-11-10-19-21(23-20)24(15-22-19)12-13-26-18-8-6-17(7-9-18)14-16-4-2-1-3-5-16/h1-11,15H,12-14H2,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibition of recombinant human leukotriene A4 hydrolase.				Bioorg Med Chem Lett 13: 1137-9 (2003) BindingDB Entry DOI: 10.7270/Q2891587
					More data for this Ligand-Target Pair