Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ceramide glucosyltransferase
(Homo sapiens (Human)) | BDBM367637
(N-((1R,2R)-1-(3-chloro-4- cyclopropoxyphenyl)-1-hy...)Show SMILES O[C@@H]([C@@H](CN1CCCC1)NC(=O)C1=NOCc2c1ccc1ccccc21)c1ccc(OC2CC2)c(Cl)c1 |r,t:13| Show InChI InChI=1S/C29H30ClN3O4/c30-24-15-19(8-12-26(24)37-20-9-10-20)28(34)25(16-33-13-3-4-14-33)31-29(35)27-22-11-7-18-5-1-2-6-21(18)23(22)17-36-32-27/h1-2,5-8,11-12,15,20,25,28,34H,3-4,9-10,13-14,16-17H2,(H,31,35)/t25-,28-/m1/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
US Patent
| Assay Description
Protein concentration was determined using BCA assay kit. Sixty micrograms of MDCK cell lysate was incubated with various concentrations of a compoun... |
US Patent US10759769 (2020)
BindingDB Entry DOI: 10.7270/Q2GT5R8T |
More data for this
Ligand-Target Pair | |
Ceramide glucosyltransferase
(Homo sapiens (Human)) | BDBM367637
(N-((1R,2R)-1-(3-chloro-4- cyclopropoxyphenyl)-1-hy...)Show SMILES O[C@@H]([C@@H](CN1CCCC1)NC(=O)C1=NOCc2c1ccc1ccccc21)c1ccc(OC2CC2)c(Cl)c1 |r,t:13| Show InChI InChI=1S/C29H30ClN3O4/c30-24-15-19(8-12-26(24)37-20-9-10-20)28(34)25(16-33-13-3-4-14-33)31-29(35)27-22-11-7-18-5-1-2-6-21(18)23(22)17-36-32-27/h1-2,5-8,11-12,15,20,25,28,34H,3-4,9-10,13-14,16-17H2,(H,31,35)/t25-,28-/m1/s1 | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
| Assay Description
This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ... |
J Med Chem 51: 1319-23 (2008)
BindingDB Entry DOI: 10.7270/Q2G44SK0 |
More data for this
Ligand-Target Pair | |