Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50106972
(4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propy...)Show SMILES O[C@@H](CNCCc1ccc(NC2CCN(CC2)C(=O)NCc2ccc(F)cc2F)cc1)COc1ccc(O)cc1 Show InChI InChI=1S/C30H36F2N4O4/c31-23-4-3-22(29(32)17-23)18-34-30(39)36-15-12-25(13-16-36)35-24-5-1-21(2-6-24)11-14-33-19-27(38)20-40-28-9-7-26(37)8-10-28/h1-10,17,25,27,33,35,37-38H,11-16,18-20H2,(H,34,39)/t27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 460 | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
In vitro agonistic activity assessed by measurement of cAMP accumulation level in CHO cells expressing human beta1-AR receptor |
Bioorg Med Chem Lett 11: 3123-7 (2001)
BindingDB Entry DOI: 10.7270/Q26D5S92 |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50106972
(4-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propy...)Show SMILES O[C@@H](CNCCc1ccc(NC2CCN(CC2)C(=O)NCc2ccc(F)cc2F)cc1)COc1ccc(O)cc1 Show InChI InChI=1S/C30H36F2N4O4/c31-23-4-3-22(29(32)17-23)18-34-30(39)36-15-12-25(13-16-36)35-24-5-1-21(2-6-24)11-14-33-19-27(38)20-40-28-9-7-26(37)8-10-28/h1-10,17,25,27,33,35,37-38H,11-16,18-20H2,(H,34,39)/t27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description
In vitro agonistic activity assessed by measurement of cAMP accumulation level in CHO cells expressing human beta3-AR receptor |
Bioorg Med Chem Lett 11: 3123-7 (2001)
BindingDB Entry DOI: 10.7270/Q26D5S92 |
More data for this
Ligand-Target Pair | |