Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50071277
(CHEMBL67251 | N-(4-{2-[(S)-2-Hydroxy-3-(pyridin-3-...)Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccccc2)cc1)COc1cccnc1 Show InChI InChI=1S/C22H25N3O4S/c26-20(17-29-21-5-4-13-23-16-21)15-24-14-12-18-8-10-19(11-9-18)25-30(27,28)22-6-2-1-3-7-22/h1-11,13,16,20,24-26H,12,14-15,17H2/t20-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Evaluated for its agonist activity and the binding affinity against human Beta-2 adrenergic receptor in membranes from chinese hamster ovary cell |
Bioorg Med Chem Lett 8: 2111-6 (1999)
BindingDB Entry DOI: 10.7270/Q2H41QKB |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50071277
(CHEMBL67251 | N-(4-{2-[(S)-2-Hydroxy-3-(pyridin-3-...)Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccccc2)cc1)COc1cccnc1 Show InChI InChI=1S/C22H25N3O4S/c26-20(17-29-21-5-4-13-23-16-21)15-24-14-12-18-8-10-19(11-9-18)25-30(27,28)22-6-2-1-3-7-22/h1-11,13,16,20,24-26H,12,14-15,17H2/t20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Evaluated for its agonist activity and the binding affinity against human Beta-1 adrenergic receptor in membranes from chinese hamster ovary cell |
Bioorg Med Chem Lett 8: 2111-6 (1999)
BindingDB Entry DOI: 10.7270/Q2H41QKB |
More data for this
Ligand-Target Pair | |
Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50071277
(CHEMBL67251 | N-(4-{2-[(S)-2-Hydroxy-3-(pyridin-3-...)Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccccc2)cc1)COc1cccnc1 Show InChI InChI=1S/C22H25N3O4S/c26-20(17-29-21-5-4-13-23-16-21)15-24-14-12-18-8-10-19(11-9-18)25-30(27,28)22-6-2-1-3-7-22/h1-11,13,16,20,24-26H,12,14-15,17H2/t20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Evaluated for its agonist activity against human Beta-3 adrenergic receptor |
Bioorg Med Chem Lett 8: 2111-6 (1999)
BindingDB Entry DOI: 10.7270/Q2H41QKB |
More data for this
Ligand-Target Pair | |