Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 340.2 BDBM282749

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM282749 (US9884843, Compound 93) Show SMILES O[C@@H]1c2c(ccc(OCC3CC3)c2C(F)F)S(=O)(=O)C1(F)F Show InChI InChI=1S/C13H12F4O4S/c14-12(15)9-7(21-5-6-1-2-6)3-4-8-10(9)11(18)13(16,17)22(8,19)20/h3-4,6,11-12,18H,1-2,5H2/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	7.5	n/a
PELOTON THERAPEUTICS, INC. US Patent					Assay Description The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...				US Patent US9884843 (2018) BindingDB Entry DOI: 10.7270/Q2HQ41Z0
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