Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 385.2 BDBM566617

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM566617 (3-fluoro-5-(((1R,2aR)-1,3,3,4,4-pentafluoro-2a- hy...) Show SMILES O[C@]12C[C@@H](F)c3c1c(ccc3Oc1cc(F)cc(c1)C#N)C(F)(F)C2(F)F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
TBA					Assay Description The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...				Citation and Details BindingDB Entry DOI: 10.7270/Q2474F3H
					More data for this Ligand-Target Pair