Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440962
(US10639284, Compound 3.131 | US11426364, Compound ...)Show SMILES OC(=O)[C@H]1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3ccccc3F)cc2OCc2cncc(c2)C#N)C1 |r| Show InChI InChI=1S/C34H29ClFN3O4/c35-29-13-24(19-39-11-10-23(18-39)34(40)41)32(42-20-22-12-21(15-37)16-38-17-22)14-33(29)43-31-9-8-26-25(5-3-6-28(26)31)27-4-1-2-7-30(27)36/h1-7,12-14,16-17,23,31H,8-11,18-20H2,(H,40,41)/t23-,31-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2K93BSK |
More data for this
Ligand-Target Pair | |
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440962
(US10639284, Compound 3.131 | US11426364, Compound ...)Show SMILES OC(=O)[C@H]1CCN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3ccccc3F)cc2OCc2cncc(c2)C#N)C1 |r| Show InChI InChI=1S/C34H29ClFN3O4/c35-29-13-24(19-39-11-10-23(18-39)34(40)41)32(42-20-22-12-21(15-37)16-38-17-22)14-33(29)43-31-9-8-26-25(5-3-6-28(26)31)27-4-1-2-7-30(27)36/h1-7,12-14,16-17,23,31H,8-11,18-20H2,(H,40,41)/t23-,31-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA... |
US Patent US10639284 (2020)
BindingDB Entry DOI: 10.7270/Q25Q5043 |
More data for this
Ligand-Target Pair | |