Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
RNA-directed RNA polymerase
(Hepatitis C virus) | BDBM50137869
(2,4-Dioxo-4-pyridin-3-yl-butyric acid | CHEMBL1779...)Show InChI InChI=1S/C9H7NO4/c11-7(4-8(12)9(13)14)6-2-1-3-10-5-6/h1-3,5H,4H2,(H,13,14) | PDB
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Italy. Vinc
Curated by ChEMBL
| Assay Description Inhibitory activity against Hepatitis C virus RNA dependent RNA polymerase nonstructural protein 5B |
J Med Chem 47: 14-7 (2003)
Article DOI: 10.1021/jm0342109 BindingDB Entry DOI: 10.7270/Q2736QB8 |
More data for this Ligand-Target Pair | |
Polymerase acidic protein
(Hepatitis C virus) | BDBM50137869
(2,4-Dioxo-4-pyridin-3-yl-butyric acid | CHEMBL1779...)Show InChI InChI=1S/C9H7NO4/c11-7(4-8(12)9(13)14)6-2-1-3-10-5-6/h1-3,5H,4H2,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center
Curated by ChEMBL
| Assay Description Plaque growth inhibition |
ACS Chem Biol 7: 526-34 (2012)
Article DOI: 10.1021/cb200439z BindingDB Entry DOI: 10.7270/Q2JQ121G |
More data for this Ligand-Target Pair | |