Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neprilysin [1-24]
(Sus scrofa) | BDBM50298106
(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)Show InChI InChI=1S/C13H14F3NO3S/c14-13(15,16)10(21)7-11(18)17-9(12(19)20)6-8-4-2-1-3-5-8/h1-5,9-10,21H,6-7H2,(H,17,18)(H,19,20) | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Chimica
Curated by ChEMBL
| Assay Description Inhibition of pig kidney NEP by fluorimetry |
Bioorg Med Chem Lett 19: 4715-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50298106
(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)Show InChI InChI=1S/C13H14F3NO3S/c14-13(15,16)10(21)7-11(18)17-9(12(19)20)6-8-4-2-1-3-5-8/h1-5,9-10,21H,6-7H2,(H,17,18)(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Chimica
Curated by ChEMBL
| Assay Description Inhibition of human recombinant ACE by fluorimetry |
Bioorg Med Chem Lett 19: 4715-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT |
More data for this Ligand-Target Pair | |
Endothelin-converting enzyme 1
(Homo sapiens (Human)) | BDBM50298106
(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)Show InChI InChI=1S/C13H14F3NO3S/c14-13(15,16)10(21)7-11(18)17-9(12(19)20)6-8-4-2-1-3-5-8/h1-5,9-10,21H,6-7H2,(H,17,18)(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Chimica
Curated by ChEMBL
| Assay Description Inhibition of human recombinant ECE1 by fluorimetry |
Bioorg Med Chem Lett 19: 4715-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.064 BindingDB Entry DOI: 10.7270/Q2GH9JWT |
More data for this Ligand-Target Pair | |