Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 734.5 BDBM50285688

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50285688 ((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...) Show SMILES OC(=O)CC1(CS[C@H](CCc2ccccc2C(O)(C(F)(F)F)C(F)(F)F)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C33H27Cl2F6NO3S2/c34-27-28-25(47-29(27)35)13-11-22(42-28)10-8-19-4-3-6-21(16-19)24(46-18-30(14-15-30)17-26(43)44)12-9-20-5-1-2-7-23(20)31(45,32(36,37)38)33(39,40)41/h1-8,10-11,13,16,24,45H,9,12,14-15,17-18H2,(H,43,44)/b10-8+/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.42	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes				Bioorg Med Chem Lett 5: 2551-2556 (1995) Article DOI: 10.1016/0960-894X(95)00448-3 BindingDB Entry DOI: 10.7270/Q2W37W8Q
					More data for this Ligand-Target Pair