Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50066944
(CHEMBL3401692)Show SMILES OC(=O)CCCN1CCOc2c(NC(=O)c3ccc(OCCCCc4ccccc4)cc3)cccc12 Show InChI InChI=1S/C29H32N2O5/c32-27(33)13-7-18-31-19-21-36-28-25(11-6-12-26(28)31)30-29(34)23-14-16-24(17-15-23)35-20-5-4-10-22-8-2-1-3-9-22/h1-3,6,8-9,11-12,14-17H,4-5,7,10,13,18-21H2,(H,30,34)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat... |
Bioorg Med Chem 23: 2079-97 (2015)
Article DOI: 10.1016/j.bmc.2015.03.011
BindingDB Entry DOI: 10.7270/Q2SB47FF |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 2
(Homo sapiens (Human)) | BDBM50066944
(CHEMBL3401692)Show SMILES OC(=O)CCCN1CCOc2c(NC(=O)c3ccc(OCCCCc4ccccc4)cc3)cccc12 Show InChI InChI=1S/C29H32N2O5/c32-27(33)13-7-18-31-19-21-36-28-25(11-6-12-26(28)31)30-29(34)23-14-16-24(17-15-23)35-20-5-4-10-22-8-2-1-3-9-22/h1-3,6,8-9,11-12,14-17H,4-5,7,10,13,18-21H2,(H,30,34)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat... |
Bioorg Med Chem 23: 2079-97 (2015)
Article DOI: 10.1016/j.bmc.2015.03.011
BindingDB Entry DOI: 10.7270/Q2SB47FF |
More data for this
Ligand-Target Pair | |