Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM50013538
(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)Show InChI InChI=1S/C20H19NO4/c22-20(23)9-4-12-24-17-6-3-7-18(13-17)25-14-16-11-10-15-5-1-2-8-19(15)21-16/h1-3,5-8,10-11,13H,4,9,12,14H2,(H,22,23) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research
Curated by ChEMBL
| Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM) |
J Med Chem 33: 1186-94 (1990)
BindingDB Entry DOI: 10.7270/Q2TB15WM |
More data for this Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50013538
(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)Show InChI InChI=1S/C20H19NO4/c22-20(23)9-4-12-24-17-6-3-7-18(13-17)25-14-16-11-10-15-5-1-2-8-19(15)21-16/h1-3,5-8,10-11,13H,4,9,12,14H2,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research
Curated by ChEMBL
| Assay Description In vitro binding affinity against cysteinyl leukotriene D4 receptor from guinea pig lung membrane |
J Med Chem 33: 2828-41 (1990)
BindingDB Entry DOI: 10.7270/Q29C6WDM |
More data for this Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50013538
(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)Show InChI InChI=1S/C20H19NO4/c22-20(23)9-4-12-24-17-6-3-7-18(13-17)25-14-16-11-10-15-5-1-2-8-19(15)21-16/h1-3,5-8,10-11,13H,4,9,12,14H2,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research
Curated by ChEMBL
| Assay Description Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips. |
J Med Chem 33: 1186-94 (1990)
BindingDB Entry DOI: 10.7270/Q2TB15WM |
More data for this Ligand-Target Pair | |