Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Integrin alpha-2/beta-3
(Homo sapiens (Human)) | BDBM50354351
(CHEMBL1836345)Show SMILES OC(=O)CCN1Cc2ccc(NC(=O)c3ccc(cc3)C3CCNCC3)cc2C1=O Show InChI InChI=1S/C23H25N3O4/c27-21(28)9-12-26-14-18-5-6-19(13-20(18)23(26)30)25-22(29)17-3-1-15(2-4-17)16-7-10-24-11-8-16/h1-6,13,16,24H,7-12,14H2,(H,25,29)(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine
Curated by ChEMBL
| Assay Description Displacement of FITC-labeled fibrinogen from alpha2beta3 in human platelets |
Bioorg Med Chem Lett 21: 5971-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.063 BindingDB Entry DOI: 10.7270/Q26Q1XNS |
More data for this Ligand-Target Pair | |
Integrin alpha-IIb/beta-3
(Homo sapiens (Human)) | BDBM50354351
(CHEMBL1836345)Show SMILES OC(=O)CCN1Cc2ccc(NC(=O)c3ccc(cc3)C3CCNCC3)cc2C1=O Show InChI InChI=1S/C23H25N3O4/c27-21(28)9-12-26-14-18-5-6-19(13-20(18)23(26)30)25-22(29)17-3-1-15(2-4-17)16-7-10-24-11-8-16/h1-6,13,16,24H,7-12,14H2,(H,25,29)(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine
Curated by ChEMBL
| Assay Description Inhibition of FITC-labeled fibrinogen binding to integrin alpha2bbeta3 receptor in human platelets by flow cytometry |
Bioorg Med Chem 21: 4646-61 (2013)
Article DOI: 10.1016/j.bmc.2013.05.019 BindingDB Entry DOI: 10.7270/Q2Q81FGX |
More data for this Ligand-Target Pair | |