Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354666
(CHEMBL1833979)Show SMILES OC(=O)CCc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C19H18BrFN4O4S/c20-12-2-1-10(21)9-13(12)29-11-5-7-25(8-6-11)19-24-17-16(30-19)18(28)23-14(22-17)3-4-15(26)27/h1-2,9,11H,3-8H2,(H,26,27)(H,22,23,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 168 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in rat Hep cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354666
(CHEMBL1833979)Show SMILES OC(=O)CCc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C19H18BrFN4O4S/c20-12-2-1-10(21)9-13(12)29-11-5-7-25(8-6-11)19-24-17-16(30-19)18(28)23-14(22-17)3-4-15(26)27/h1-2,9,11H,3-8H2,(H,26,27)(H,22,23,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 266 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354666
(CHEMBL1833979)Show SMILES OC(=O)CCc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C19H18BrFN4O4S/c20-12-2-1-10(21)9-13(12)29-11-5-7-25(8-6-11)19-24-17-16(30-19)18(28)23-14(22-17)3-4-15(26)27/h1-2,9,11H,3-8H2,(H,26,27)(H,22,23,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |