Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Integrin alpha-2/beta-3
(Homo sapiens (Human)) | BDBM50354348
(CHEMBL1836342)Show SMILES OC(=O)CN1Cc2ccc(NC(=O)c3ccc(cc3)C3CCNCC3)cc2C1=O Show InChI InChI=1S/C22H23N3O4/c26-20(27)13-25-12-17-5-6-18(11-19(17)22(25)29)24-21(28)16-3-1-14(2-4-16)15-7-9-23-10-8-15/h1-6,11,15,23H,7-10,12-13H2,(H,24,28)(H,26,27) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine
Curated by ChEMBL
| Assay Description
Displacement of FITC-labeled fibrinogen from alpha2beta3 in human platelets |
Bioorg Med Chem Lett 21: 5971-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.063
BindingDB Entry DOI: 10.7270/Q26Q1XNS |
More data for this
Ligand-Target Pair | |
Integrin alpha-IIb/beta-3
(Homo sapiens (Human)) | BDBM50354348
(CHEMBL1836342)Show SMILES OC(=O)CN1Cc2ccc(NC(=O)c3ccc(cc3)C3CCNCC3)cc2C1=O Show InChI InChI=1S/C22H23N3O4/c26-20(27)13-25-12-17-5-6-18(11-19(17)22(25)29)24-21(28)16-3-1-14(2-4-16)15-7-9-23-10-8-15/h1-6,11,15,23H,7-10,12-13H2,(H,24,28)(H,26,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-labeled fibrinogen binding to integrin alpha2bbeta3 receptor in human platelets by flow cytometry |
Bioorg Med Chem 21: 4646-61 (2013)
Article DOI: 10.1016/j.bmc.2013.05.019
BindingDB Entry DOI: 10.7270/Q2Q81FGX |
More data for this
Ligand-Target Pair | |