Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Integrin alpha-2/beta-3
(Homo sapiens (Human)) | BDBM50354349
(CHEMBL1836343)Show SMILES OC(=O)CN1Cc2ccc(NC(=O)c3ccc4CCNCc4c3)cc2C1=O Show InChI InChI=1S/C20H19N3O4/c24-18(25)11-23-10-14-3-4-16(8-17(14)20(23)27)22-19(26)13-2-1-12-5-6-21-9-15(12)7-13/h1-4,7-8,21H,5-6,9-11H2,(H,22,26)(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine
Curated by ChEMBL
| Assay Description
Displacement of FITC-labeled fibrinogen from alpha2beta3 in human platelets |
Bioorg Med Chem Lett 21: 5971-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.063
BindingDB Entry DOI: 10.7270/Q26Q1XNS |
More data for this
Ligand-Target Pair | |
Integrin alpha-IIb/beta-3
(Homo sapiens (Human)) | BDBM50354349
(CHEMBL1836343)Show SMILES OC(=O)CN1Cc2ccc(NC(=O)c3ccc4CCNCc4c3)cc2C1=O Show InChI InChI=1S/C20H19N3O4/c24-18(25)11-23-10-14-3-4-16(8-17(14)20(23)27)22-19(26)13-2-1-12-5-6-21-9-15(12)7-13/h1-4,7-8,21H,5-6,9-11H2,(H,22,26)(H,24,25) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine
Curated by ChEMBL
| Assay Description
Inhibition of FITC-labeled fibrinogen binding to integrin alpha2bbeta3 receptor in human platelets by flow cytometry |
Bioorg Med Chem 21: 4646-61 (2013)
Article DOI: 10.1016/j.bmc.2013.05.019
BindingDB Entry DOI: 10.7270/Q2Q81FGX |
More data for this
Ligand-Target Pair | |