Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 425.2 BDBM50437293

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM50437293 (CHEMBL2407486) Show SMILES OC(=O)CSc1nnc(-c2ccc(cc2)[N+]([O-])=O)n1-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H10Cl2N4O4S/c17-12-6-5-11(7-13(12)18)21-15(19-20-16(21)27-8-14(23)24)9-1-3-10(4-2-9)22(25)26/h1-7H,8H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.78E+5	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to human RPA70N assessed as inhibition of interaction with FITC-Ahx-DFTADDLEELDTLAS-NH2 after 1 hr by fluorescence polarization anis...				ACS Med Chem Lett 4: 601-605 (2013) Article DOI: 10.1021/ml400032y BindingDB Entry DOI: 10.7270/Q22N53PW
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