Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50356908
(CHEMBL1915557)Show SMILES OC(=O)Cn1nnc(n1)-c1cc(no1)-c1cn(Cc2cc(Br)c(Br)c(Br)c2)nn1 Show InChI InChI=1S/C15H9Br3N8O3/c16-8-1-7(2-9(17)14(8)18)4-25-5-11(19-23-25)10-3-12(29-22-10)15-20-24-26(21-15)6-13(27)28/h1-3,5H,4,6H2,(H,27,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD by rat microsomal assay |
Bioorg Med Chem Lett 21: 6505-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.073
BindingDB Entry DOI: 10.7270/Q2VQ332W |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50356908
(CHEMBL1915557)Show SMILES OC(=O)Cn1nnc(n1)-c1cc(no1)-c1cn(Cc2cc(Br)c(Br)c(Br)c2)nn1 Show InChI InChI=1S/C15H9Br3N8O3/c16-8-1-7(2-9(17)14(8)18)4-25-5-11(19-23-25)10-3-12(29-22-10)15-20-24-26(21-15)6-13(27)28/h1-3,5H,4,6H2,(H,27,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 212 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs b... |
Bioorg Med Chem Lett 21: 6505-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.073
BindingDB Entry DOI: 10.7270/Q2VQ332W |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50356908
(CHEMBL1915557)Show SMILES OC(=O)Cn1nnc(n1)-c1cc(no1)-c1cn(Cc2cc(Br)c(Br)c(Br)c2)nn1 Show InChI InChI=1S/C15H9Br3N8O3/c16-8-1-7(2-9(17)14(8)18)4-25-5-11(19-23-25)10-3-12(29-22-10)15-20-24-26(21-15)6-13(27)28/h1-3,5H,4,6H2,(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acid |
Bioorg Med Chem Lett 21: 6505-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.073
BindingDB Entry DOI: 10.7270/Q2VQ332W |
More data for this
Ligand-Target Pair | |