Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50356906
(CHEMBL1915555)Show SMILES OC(=O)Cn1nnc(n1)-c1cncc(c1)-c1cn(Cc2cc(Br)c(Br)c(Br)c2)nn1 Show InChI InChI=1S/C17H11Br3N8O2/c18-12-1-9(2-13(19)16(12)20)6-27-7-14(22-25-27)10-3-11(5-21-4-10)17-23-26-28(24-17)8-15(29)30/h1-5,7H,6,8H2,(H,29,30) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD by rat microsomal assay |
Bioorg Med Chem Lett 21: 6505-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.073
BindingDB Entry DOI: 10.7270/Q2VQ332W |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50356906
(CHEMBL1915555)Show SMILES OC(=O)Cn1nnc(n1)-c1cncc(c1)-c1cn(Cc2cc(Br)c(Br)c(Br)c2)nn1 Show InChI InChI=1S/C17H11Br3N8O2/c18-12-1-9(2-13(19)16(12)20)6-27-7-14(22-25-27)10-3-11(5-21-4-10)17-23-26-28(24-17)8-15(29)30/h1-5,7H,6,8H2,(H,29,30) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 694 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs b... |
Bioorg Med Chem Lett 21: 6505-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.073
BindingDB Entry DOI: 10.7270/Q2VQ332W |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50356906
(CHEMBL1915555)Show SMILES OC(=O)Cn1nnc(n1)-c1cncc(c1)-c1cn(Cc2cc(Br)c(Br)c(Br)c2)nn1 Show InChI InChI=1S/C17H11Br3N8O2/c18-12-1-9(2-13(19)16(12)20)6-27-7-14(22-25-27)10-3-11(5-21-4-10)17-23-26-28(24-17)8-15(29)30/h1-5,7H,6,8H2,(H,29,30) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acid |
Bioorg Med Chem Lett 21: 6505-9 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.073
BindingDB Entry DOI: 10.7270/Q2VQ332W |
More data for this
Ligand-Target Pair | |