Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50364039
(CHEMBL1950549)Show SMILES OC(=O)Cn1nnc(n1)-c1nnc(OCCCOc2cc(F)ccc2Br)s1 Show InChI InChI=1S/C14H12BrFN6O4S/c15-9-3-2-8(16)6-10(9)25-4-1-5-26-14-19-18-13(27-14)12-17-21-22(20-12)7-11(23)24/h2-3,6H,1,4-5,7H2,(H,23,24) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibition of rat liver microsome SCD1 |
Bioorg Med Chem Lett 22: 623-7 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.070 BindingDB Entry DOI: 10.7270/Q26M379R |
More data for this Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50364039
(CHEMBL1950549)Show SMILES OC(=O)Cn1nnc(n1)-c1nnc(OCCCOc2cc(F)ccc2Br)s1 Show InChI InChI=1S/C14H12BrFN6O4S/c15-9-3-2-8(16)6-10(9)25-4-1-5-26-14-19-18-13(27-14)12-17-21-22(20-12)7-11(23)24/h2-3,6H,1,4-5,7H2,(H,23,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assay |
Bioorg Med Chem Lett 22: 623-7 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.070 BindingDB Entry DOI: 10.7270/Q26M379R |
More data for this Ligand-Target Pair | |