Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 323.2 BDBM50509171

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50509171 (CHEMBL4476501) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C18H13NO5/c20-15-10-14(19-16(17(15)21)18(22)23)11-6-8-13(9-7-11)24-12-4-2-1-3-5-12/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509171 (CHEMBL4476501) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C18H13NO5/c20-15-10-14(19-16(17(15)21)18(22)23)11-6-8-13(9-7-11)24-12-4-2-1-3-5-12/h1-10,21H,(H,19,20)(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair