Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 231.2 BDBM50509173

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein (Hepatitis C virus)	BDBM50509173 (CHEMBL4469796) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1 Show InChI InChI=1S/C12H9NO4/c14-9-6-8(7-4-2-1-3-5-7)13-10(11(9)15)12(16)17/h1-6,15H,(H,13,14)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair
Polymerase acidic protein (Hepatitis C virus)	BDBM50509173 (CHEMBL4469796) Show SMILES OC(=O)c1[nH]c(cc(=O)c1O)-c1ccccc1 Show InChI InChI=1S/C12H9NO4/c14-9-6-8(7-4-2-1-3-5-7)13-10(11(9)15)12(16)17/h1-6,15H,(H,13,14)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Influenza A virus RNA-dependent RNA polymerase PA N-terminal endonuclease using [6-FAM]AATCGCAGGCAGCACTC[TAM] substrate and measured ov...				J Med Chem 62: 9438-9449 (2019) Article DOI: 10.1021/acs.jmedchem.9b00747 BindingDB Entry DOI: 10.7270/Q27M0C7P
					More data for this Ligand-Target Pair