Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 502.3 BDBM50064067

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50064067 (6-Bromo-4-oxo-2-[4-(quinolin-2-ylmethoxy)-phenyl]-...) Show SMILES OC(=O)c1cc(Br)cc2c1oc(cc2=O)-c1ccc(OCc2ccc3ccccc3n2)cc1 Show InChI InChI=1S/C26H16BrNO5/c27-17-11-20-23(29)13-24(33-25(20)21(12-17)26(30)31)16-6-9-19(10-7-16)32-14-18-8-5-15-3-1-2-4-22(15)28-18/h1-13H,14H2,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...				Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50064067 (6-Bromo-4-oxo-2-[4-(quinolin-2-ylmethoxy)-phenyl]-...) Show SMILES OC(=O)c1cc(Br)cc2c1oc(cc2=O)-c1ccc(OCc2ccc3ccccc3n2)cc1 Show InChI InChI=1S/C26H16BrNO5/c27-17-11-20-23(29)13-24(33-25(20)21(12-17)26(30)31)16-6-9-19(10-7-16)32-14-18-8-5-15-3-1-2-4-22(15)28-18/h1-13H,14H2,(H,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	504	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]-LTD4.				J Med Chem 41: 1428-38 (1998) Article DOI: 10.1021/jm970179x BindingDB Entry DOI: 10.7270/Q21835MZ
					More data for this Ligand-Target Pair