Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 454.3 BDBM214704

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monocarboxylate transporter 1 (Rattus norvegicus (Rat))	BDBM214704 (US9296728, 28) Show SMILES OC(=O)c1cc2ccc(cc2oc1=O)N(Cc1ccc(Cl)cc1)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C24H17Cl2NO4/c25-18-6-1-15(2-7-18)13-27(14-16-3-8-19(26)9-4-16)20-10-5-17-11-21(23(28)29)24(30)31-22(17)12-20/h1-12H,13-14H2,(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	920	n/a	n/a	n/a	n/a	7.43	37
Regents of the University of Minnesota US Patent					Assay Description The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...				US Patent US9296728 (2016) BindingDB Entry DOI: 10.7270/Q2KH0M5R
					More data for this Ligand-Target Pair