Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Taste receptor type 2 member 14
(Homo sapiens (Human)) | BDBM50320146
(4-((N-benzyl-4-chlorophenylsulfonamido)methyl)benz...)Show SMILES OC(=O)c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C21H18ClNO4S/c22-19-10-12-20(13-11-19)28(26,27)23(14-16-4-2-1-3-5-16)15-17-6-8-18(9-7-17)21(24)25/h1-13H,14-15H2,(H,24,25) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| US Patent
| n/a | n/a | 394 | n/a | n/a | n/a | n/a | n/a | n/a |
Senomyx, Inc.
US Patent
| Assay Description
In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a... |
US Patent US9247759 (2016)
BindingDB Entry DOI: 10.7270/Q2V69HFW |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50320146
(4-((N-benzyl-4-chlorophenylsulfonamido)methyl)benz...)Show SMILES OC(=O)c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C21H18ClNO4S/c22-19-10-12-20(13-11-19)28(26,27)23(14-16-4-2-1-3-5-16)15-17-6-8-18(9-7-17)21(24)25/h1-13H,14-15H2,(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono SA
Curated by ChEMBL
| Assay Description
Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of IP10-induced chemotaxis after 4 hrs |
Bioorg Med Chem Lett 20: 3614-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.04.113
BindingDB Entry DOI: 10.7270/Q2668DDX |
More data for this
Ligand-Target Pair | |