Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251397
(CHEMBL480334 | endo-4-((3-(4-benzylphenylamino)-8-...)Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Cc3ccccc3)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C28H30N2O2/c31-28(32)23-10-6-22(7-11-23)19-30-26-14-15-27(30)18-25(17-26)29-24-12-8-21(9-13-24)16-20-4-2-1-3-5-20/h1-13,25-27,29H,14-19H2,(H,31,32)/t25-,26+,27- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) |
Bioorg Med Chem Lett 18: 3895-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.041
BindingDB Entry DOI: 10.7270/Q2GQ6XK8 |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251397
(CHEMBL480334 | endo-4-((3-(4-benzylphenylamino)-8-...)Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Cc3ccccc3)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C28H30N2O2/c31-28(32)23-10-6-22(7-11-23)19-30-26-14-15-27(30)18-25(17-26)29-24-12-8-21(9-13-24)16-20-4-2-1-3-5-20/h1-13,25-27,29H,14-19H2,(H,31,32)/t25-,26+,27- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase in human whole blood |
Bioorg Med Chem Lett 18: 3895-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.041
BindingDB Entry DOI: 10.7270/Q2GQ6XK8 |
More data for this
Ligand-Target Pair | |