Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251398
(CHEMBL480335 | endo-4-((3-(4-(pyridin-4-ylmethyl)p...)Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Cc3ccncc3)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C27H29N3O2/c31-27(32)22-5-1-21(2-6-22)18-30-25-9-10-26(30)17-24(16-25)29-23-7-3-19(4-8-23)15-20-11-13-28-14-12-20/h1-8,11-14,24-26,29H,9-10,15-18H2,(H,31,32)/t24-,25+,26- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) |
Bioorg Med Chem Lett 18: 3895-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.041
BindingDB Entry DOI: 10.7270/Q2GQ6XK8 |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251398
(CHEMBL480335 | endo-4-((3-(4-(pyridin-4-ylmethyl)p...)Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Cc3ccncc3)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C27H29N3O2/c31-27(32)22-5-1-21(2-6-22)18-30-25-9-10-26(30)17-24(16-25)29-23-7-3-19(4-8-23)15-20-11-13-28-14-12-20/h1-8,11-14,24-26,29H,9-10,15-18H2,(H,31,32)/t24-,25+,26- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase in human whole blood |
Bioorg Med Chem Lett 18: 3895-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.041
BindingDB Entry DOI: 10.7270/Q2GQ6XK8 |
More data for this
Ligand-Target Pair | |