Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 511.6 BDBM50251838

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50251838 (CHEMBL481531 | endo-4-((3-(4-(4-(thiazol-2-yl)phen...) Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccc(cc3)-c3nccs3)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C30H29N3O3S/c34-30(35)22-3-1-20(2-4-22)19-33-25-9-10-26(33)18-24(17-25)32-23-7-13-28(14-8-23)36-27-11-5-21(6-12-27)29-31-15-16-37-29/h1-8,11-16,24-26,32H,9-10,17-19H2,(H,34,35)/t24-,25+,26-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase (unknown origin)				Bioorg Med Chem Lett 18: 3895-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.041 BindingDB Entry DOI: 10.7270/Q2GQ6XK8
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50251838 (CHEMBL481531 | endo-4-((3-(4-(4-(thiazol-2-yl)phen...) Show SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccc(cc3)-c3nccs3)cc2)cc1 |r,THB:7:8:15.14.13:10.11| Show InChI InChI=1S/C30H29N3O3S/c34-30(35)22-3-1-20(2-4-22)19-33-25-9-10-26(33)18-24(17-25)32-23-7-13-28(14-8-23)36-27-11-5-21(6-12-27)29-31-15-16-37-29/h1-8,11-16,24-26,32H,9-10,17-19H2,(H,34,35)/t24-,25+,26-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase in human whole blood				Bioorg Med Chem Lett 18: 3895-8 (2008) Article DOI: 10.1016/j.bmcl.2008.06.041 BindingDB Entry DOI: 10.7270/Q2GQ6XK8
					More data for this Ligand-Target Pair