Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 518.6 BDBM50342776

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50342776 (4-((3-(4-(biphenyl-4-yloxy)phenylamino)-6-azabicyc...) Show SMILES OC(=O)c1ccc(CN2CC3CC(Nc4ccc(Oc5ccc(cc5)-c5ccccc5)cc4)C2CCC3)cc1 |THB:7:8:12.11:34.35.36| Show InChI InChI=1S/C34H34N2O3/c37-34(38)28-11-9-24(10-12-28)22-36-23-25-5-4-8-33(36)32(21-25)35-29-15-19-31(20-16-29)39-30-17-13-27(14-18-30)26-6-2-1-3-7-26/h1-3,6-7,9-20,25,32-33,35H,4-5,8,21-23H2,(H,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University (GNU) Curated by ChEMBL					Assay Description Inhibition of human leukotriene A4 hydrolase				Eur J Med Chem 46: 1593-603 (2011) Article DOI: 10.1016/j.ejmech.2011.02.007 BindingDB Entry DOI: 10.7270/Q2K64JDG
					More data for this Ligand-Target Pair